一、基本信息

朱俊飞，博士，讲师

电子邮箱：hbzjfp@hubu.edu.cn

研究领域：核苷类药物设计与药物靶向递送

二、教育背景

2016.09–2019.06  武汉大学，生物化学与分子生物学，理学博士

2012.09–2015.06  贵州大学，药物化学，理学硕士

2006.09–2010.06  武汉理工大学，制药工程，工学学士

三、工作经历

2023.06至今          湖北大学，省部共建生物催化与酶工程国家重点实验室，讲师

2021.01–2023.05  深圳大学，博士后

2019.10–2020.12  香港理工大学，博士后

2015.08–2016.05  武汉药明康德新药开发有限公司 研究员

2010.08–2011.08  齐鲁制药有限公司 药物合成

四、代表性论文

1. Zhu, J.; He, G., Chen, P.-H.; Zhang, Y.; Zhang, Y.; Lei, S.; Zhang, Y.; Li, M.; Huang, P.; Lin, J., Terpyridine Grafted Nitrogen Terminal Endowing Cyanine with Metal Ions-Regulated Photophysical Properties for Cancer Theranostics. Research 2023, 6, 0061.

2. Zhu, J.; Zhang, H.; Chen, K.; Li, Y.; Yang, Z.; Chen, S.; Zheng, X.; Zhou, X.; Jiang, Z.-X., Peptidic Monodisperse PEG “Comb” as Multifunctional “Add‐on” Module for Imaging-Traceable and Thermo-Responsive Theranostics. Adv. Healthcare Mater. 2020, 9, 1901331.

3. Zhu, J.; Xiao, Y.; Zhang, H.; Li, Y.; Yuan, Y.; Yang, Z.; Chen, S.; Zheng, X.; Zhou, X.; Jiang, Z.-X., Peptidic Monodisperse PEG “Combs” with Fine-Tunable LCST and Multiple Imaging Modalities. Biomacromolecules 2019, 20, 1281-1287.

4. Zhang, Y.; Chen, P.-H.; Li, B.; Guo, H.; Zhu, J.; Dang, Z.; Lei, S.; Huang, P.; Lin, J. Comprehensively Optimizing Fenton Reaction Factors for Antitumor Chemodynamic Therapy by Charge-Reversal Theranostics. ACS Nano 2023, 17, 16743 – 16756.

5. Ho, P.-Y.; Lee, S.-Y.; Kam, C.; Zhu, J.; Shan, G.-G.; Hong, Y.; Wong, W.-Y.; Chen, S., Fluorescence Imaging and Photodynamic Inactivation of Bacteria Based on Cationic Cyclometalated Iridium(III) Complexes with Aggregation-Induced Emission Properties. Adv. Healthcare Mater. 2021, 10, 2100706.

6. Zhu, J.; Li, Z.; Wang, Q.; Liu, Y.; He, J., The Contribution of Adenines in the Catalytic Core of 10-23 DNAzyme Improved by the 6-Amino Group Modifications. Bioorg. Med. Chem. Lett. 2016, 26, 4462-4465.

7. Zhu, J.; Li, Z.; Yang, Z.; He, J., Studies on the Preferred Uracil-Adenine Base Pair at the Cleavage Site of 10-23 DNAzyme by Functional Group Modifications on Adenine. Bioorg. Med. Chem. 2015, 23, 4256-4263.

8. Yang, X.; Xiao, Z.; Zhu, J.; Li, Z.; He, J.; Zhang, L.; Yang, Z., Spatial Conservation Studies of Nucleobases in 10-23 DNAzyme by 2′-Positioned Isonucleotides and Enantiomers for Increased Activity. Org. Biomol. Chem. 2016, 14, 4032-4038.

9. Li, Z.; Zhu, J.; He, J., Conformational Studies of 10-23 DNAzyme in Solution Through Pyrenyl-Labeled 2′-Deoxyadenosine Derivatives. Org. Biomol. Chem. 2016, 14, 9846-9858.

10. Liu, G.; Li, Z.; Zhu, J.; Liu, Y.; Zhou, Y.; He, J., Studies on the Thymine-Mercury-Thymine Base Pairing in Parallel and Anti-Parallel DNA Duplexes. New J. Chem. 2015, 39, 8752-8762.